In case you don't know what's a Vuvuzela, here's a pic taken from wikipedia.
This instrument is made famous when South Africa hosted the FIFA World Cup in 2010. Stadium audience blow the Vuvuzela horn to make sounds, not sure to cheer or to distract the players. There were a lot of complaints during the World Cup, about the sound being an irritation to the players, supporters, TV audiences.
Supplement information: The Adidas Jabulani ball is used as the official World Cup ball for that year. It received many criticism for its 'unpredictable behaviour'. Cristiano Ronaldo would love to use it to his advantage against goalkeepers.
Back on track, so the challenge is to remove the Vuvuzela noise from an audio clip that consists of human commentary, Vuvuzela noise, stadium sound and noise from other sources.
I will be talking about the concept and methodology that I know of to remove the Vuvuzuela sound.
The Vuvuzela gives a B-flat note and its harmonics. According to
http://www.wired.com, it has a fundamental frequency of 466.164 Hz. So you'll to filter out the fundamental frequency and its harmonics such as 932Hz, 1398Hz, 1864Hz, 2330Hz, 2796Hz, 3262Hz.... It is also recommended to filter 233Hz.
The human ear can hear from 20Hz to 20,000Hz, but the human speech only covers 400Hz to 5000Hz -
http://www.csun.edu. Hence, you can filter out frequencies below 400Hz and above 5000Hz. In my opinion, you can safely remove any frequencies above 3500Hz.
To summarize, just apply bandpass filter to allow 400Hz to 3500Hz to pass through and apply bandstop filters at 233Hz, 466Hz, 932Hz, 1398Hz, 1864Hz, 2330Hz, 2796Hz and 3262Hz. It takes trial and error and you might have to tweak here and there to get the best out of it. Good luck and have fun!